A differential expression network method identifies ankylosing spondylitis-related genes
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چکیده
منابع مشابه
Urolithiasis in ankylosing spondylitis: Correlation with Bath ankylosing spondylitis disease activity index (BASDAI), Bath ankylosing spondylitis functional index (BASFI) and Bath ankylosing spondylitis metrology index (BASMI)
Background: Increased incidence of renal stone has been reported in ankylosing spondylitis (AS), but unlike some well-known renal involvements, they have not been fully studied. The aim of this study was to investigate the association of AS with urolithiasis and also the relation between urinary stone and severity markers. Methods: One hundred-sixty three AS patients were included in a cross-s...
متن کاملTranscriptome network analysis reveals potential candidate genes for ankylosing spondylitis.
OBJECTIVES Ankylosing spondylitis (AS) is a chronic, inflammatory arthritis and autoimmune disease. BACKGROUND The main symptom of AS is inflammatory spinal pain; with time, some patients develop ankylosis and spinal immobility. We aim to find cure available for ankylosing spondylitis. MATERIALS AND METHODS We used the GSE11886 series to identify potential genes that related to AS to constr...
متن کاملAnkylosing Spondylitis: From Cells to Genes
Ankylosing spondylitis (AS) is a chronic inflammatory disease of unknown etiology, though it is considered an autoimmune disease. HLA-B27 is the risk factor most often associated with AS, and although the mechanism of involvement is unclear, the subtypes and other features of the relationship between HLA-B27 and AS have been studied for years. Additionally, the key role of IL-17 and Th17 cells ...
متن کاملASSOCIATION OF HLA-B27 WITH ANKYLOSING SPONDYLITIS IN ISFAHAN, IRAN
Using a standard microcytotoxicity (NIH) technique of tissue typing, the HLA-B27 antigen was identified in 30 out of 34 patients (HH.2%) with classical ankylosing spondylitis (AS), compared to 6 out of 70 controls (H.6%) (P < 0.005). We also found this antigen in 8 out of 76 (10.5%) patients with non-AS arthritis.
متن کاملAnkylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Metrology
The objective of this study was to determine the prevalence and risk factors of low bone mineral density (BMD) in patients with Spondylarthropathies (SpA) at an early stage of disease. In this cross-sectional study, the BMD of lumbar spine and hips was measured in 130 consecutive early SpA patients. The outcome measure BMD was defined as (1) osteoporosis, (2) osteopenia and (3) normal bone dens...
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ژورنال
عنوان ژورنال: Journal of Cancer Research and Therapeutics
سال: 2018
ISSN: 0973-1482
DOI: 10.4103/0973-1482.188294